ESTABLISHMENT OF A VASCULAR GRAFT INFECTION MODEL IN THE SHEEP CAROTID-ARTERY

被引：7

作者：

FLETCHER, JP

DRYDEN, M

MUNRO, R

XU, JH

HEHIR, MD

机构：

[1] Departments of Surgery, Westmead Hospital, Westmead, New South Wales

[2] Westmead Hospital, Westmead, New South Wales

来源：

AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY | 1990年 / 60卷 / 10期

关键词：

dacron; infection; polytetrafluoroethylene; staphylococcus aureus; vascular prosthesis;

D O I：

10.1111/j.1445-2197.1990.tb07477.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

A study was performed to assess whether a model of vascular graft infection could be established in sheep carotid artery. Either a protein sealed Dacron or a polytetrafluoroethylene (PTEE) graft was used in 22 sheep while a control operation was performed on 4 animals. Staphylococcus aureus in concentrations of 102, 104, 106 or 108 colony‐forming units (CFU) was inoculated into the wound before closure. No infection occurred with an inoculum of 102. The lowest concentration of organism producing infection was 104 for PTEE, 106 for Dacron and 108 for controls. Six of eleven Dacron grafts and seven of ten PTFE grafts became infected. The sheep carotid artery has proven a satisfactory model for studies of vascular graft infection. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：801 / 803

页数：3

共 13 条

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