ASYMMETRIC-SYNTHESIS OF THE C-1-C-8 FRAGMENT OF LEUKOTRIENE-B4 AND C-11-C-20 FRAGMENTS OF LEUKOTRIENE-B4 AND 12(S)-HYDROXY-5,8,14(Z),10(E)-EICOSATETRAENOIC ACID

被引：22

作者：

SOLLADIE, G

HAMDOUCHI, C

ZIANICHERIF, C

机构：

[1] Ecole Européenne des Hautes Etudes des Industries Chimiques (URA 466)

来源：

TETRAHEDRON-ASYMMETRY | 1991年 / 2卷 / 06期

关键词：

D O I：

10.1016/S0957-4166(00)82171-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An asymmetric synthesis of the C-1-C-8 fragment of LTB4 based on the reduction of optically active beta-ketosulfoxides is described as well as the asymmetric synthesis of the C-11-C-20 fragments of LTB4 and 12(S)-hydroxy-5,8,14(Z), 10(E) eicosatetraenoic acid (12-HETE) from optically active alpha-sulfinyl expxides.

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页码：457 / 469

页数：13

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