REDUCTIVE CLEAVAGE AS A ROUTE TO CARBOHYDRATE ENOLATES - APPLICATIONS TO THE SYNTHESIS OF C-LINKED DISACCHARIDES

被引：27

作者：

BINCH, HM

GRIFFIN, AM

SCHWIDETZKY, S

RAMSAY, MVJ

GALLAGHER, T

LICHTENTHALER, FW

机构：

[1] UNIV BRISTOL,SCH CHEM,BRISTOL BS8 1TS,AVON,ENGLAND

[2] TH DARMSTADT,INST ORGAN CHEM,D-64287 DARMSTADT,GERMANY

[3] GLAXO GRP RES LTD,RES & DEV,DEPT MED CHEM,GREENFORD UB6 0HE,MIDDX,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1995年 / 09期

关键词：

D O I：

10.1039/c39950000967

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The carbohydrate-derived alpha-bromo ketones 4 and 5 undergo reductive cleavage using either Zn-Cu or CeCl3-Nal and the resulting enolates are trapped by carbohydrate-based aldehydes 6, 7 and 14 to give C-disaccharide derivatives.

引用

页码：967 / 968

页数：2

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