LAT (LIDOCAINE-ADRENALINE-TETRACAINE) VERSUS TAC (TETRACAINE-ADRENALINE-COCAINE) FOR TOPICAL ANESTHESIA IN FACE AND SCALP LACERATIONS

被引：32

作者：

ERNST, AA

MARVEZVALLS, E

NICK, TG

WEISS, SJ

机构：

[1] Louisiana State University, Department, Medicine Section of Emergency Medicine, New Orleans, LA

[2] the University of Mississippi School of Health Related Professions, New Orleans, LA

来源：

AMERICAN JOURNAL OF EMERGENCY MEDICINE | 1995年 / 13卷 / 02期

关键词：

TOPICALS; ANESTHETICS; LACERATIONS;

D O I：

10.1016/0735-6757(95)90082-9

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The study objective was to compare the topical anesthetic LAT (4% lidocaine, 1:2,000 adrenaline, 1% tetracaine) to TAC (0,5% tetracaine, 1:2,000 adrenaline, 11.8% cocaine) far efficacy, adverse effects, and costs, The study design was a randomized, prospective, double blind clinical trial set in an inner-city emergency department with an emergency medicine residency program, Adults with linear lacerations of the face or scalp were eligible for inclusion in the study. Patients had lacerations anesthetized with topical TAG or LAT according to a random numbers table, A total of 95 patients were included in the study with 47 receiving TAG and 48 receiving LAT. Patients stated the number of sutures causing pain and patients and physicians rated the overall pain of suturing using a standard visual analog scale (VAS). The power of the study to determine a ranked sum difference of 15 was 0.8. Visual analog scale results and number and percentage of sutures causing pain were compared using Wilcoxon's Rank Sum Test, According to patients, the percentage of sutures causing pain was significantly fewer for LAT than TAC (P = .036, Interquartile Range 0.13 to 0.0 for LAT, 0.25 to 0 for TAG), Physicians found LAT statistically more effective than TAC (P = .0093, Interquartile Range 1 to 0 for LAT, 2 to 0 for TAG) but patients did not report a difference (P = .266, Interquartile Range 1 to 0 for both LAT and TAG), Our cost per application was $3.00 for LAT compared to $35.00 for TAG. Follow-up was accomplished in 91 of 95 patients (95%) with no reported complications for either medication, In conclusion, LAT worked at least as effectively as TAC for topical anesthesia in facial and scalp lacerations, Considering the advantages of a noncontrolled substance and less expense, LAT seems to be better suited than TAC for topical anesthesia in laceration repair. Copyright (C) 1995 hy W.B. Saunders Company

引用

页码：151 / 154

页数：4

共 42 条

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