HEPATIC MYELOPATHY - AN UNUSUAL NEUROLOGICAL COMPLICATION OF ADVANCED HEPATIC-DISEASE

被引:19
作者
SOBUKAWA, E
SAKIMURA, K
HOSHINO, S
HOSHINO, M
MIYOSHI, K
机构
[1] Department of Internal Medicine, Omiya Red Cross Hospital
关键词
LIVER CIRRHOSIS; DEMYELINATION; SPASTIC PARAPRAGIA;
D O I
10.2169/internalmedicine.33.718
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Encephalopathy is widely known as one of the neurological complications of chronic hepatic disease. Recently, the occurrence of progressive myelopathy in patients with advanced hepatic disease has been well documented and differentiated from encephalopathy. We describe a 76-year-old man with decompensatory liver cirrhosis due to hepatitis C virus infection who suffered from progressive paraplegia. Postmortem examination revealed demyelination of the lateral column of the spinal cord, especially of the thoracic segment. No evidence of spontaneous portosystemic shunts was found. These findings suggest that the patient had been affected with hepatic myelopathy, which is a rare complication of liver cirrhosis.
引用
收藏
页码:718 / 722
页数:5
相关论文
共 25 条
[1]  
Leigh A.D., Card W.I., A case associated with posterio-lateral column degeneration, J Neuropathol Exp Neurol, 8, (1949)
[2]  
Plum F., Hindfelt B., 27, (1978)
[3]  
Brown I.A., Liver-Brain Relationships. Charles C Thomas, Springfield, (1957)
[4]  
Pant S.S., Bhargava A.N., Singh M.M., Et al., Myelopathy in hepatic cirrhosis, Br Med J, 1, (1963)
[5]  
Liversedge L.A., Rawson M.D., Myelopathy in hepatic disease and portosystemic venous anastomosis, Lancet, 1, (1966)
[6]  
Victor M., Adams R.D., Cole M., The acquired (non-Wilsonian) type of chronic hepatocerebral degeneration, Medicine (Baltimore), 44, (1965)
[7]  
Pant S.S., Rebeiz J.J., Richardson E.P., Spastic paraparesis following portocaval shunts, Neurology, 18, (1968)
[8]  
Shutz R.M., Brunner L., Sanpradit M., Et al., Myelopathie bei Leber cirrhose, Acta Hepato-Splenol, 12, (1965)
[9]  
Fukuda S., Hirayama K., Advances in Neurological Science, 18, (1974)
[10]  
Giangaspeno F., Dondi C., Scarani P., Et al., Degeneration of the corticospinal tract following portosystemic shunt associated with spinal cord infarction, Virchows Arch [A], 406, (1985)