DOES ESTRADIOL STIMULATE INVIVO PRODUCTION OF 1,25-DIHYDROXYVITAMIN D-3 IN RAT

被引：32

作者：

BAKSI, SN

KENNY, AD

机构：

[1] Department of Pharmacology, Therapeutics Texas Tech University School of Medicine Lubbock

来源：

LIFE SCIENCES | 1978年 / 22卷 / 09期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0024-3205(78)90248-5

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Female rats were injected with estradiol benzoate (3 mg/kg daily) or corn oil for 8 days before receiving 325 picomoles of 25-[26,273H]-hydroxyvitamin D3 intravenously. Eighteen hours later lipids were extracted from plasma, gut mucosa and kidneys and vitamin D3 metabolites were separated using Sephadex LH-20 and chloroform: hexanes (65:35) column chromatography. Estradiol treatment increased 1,25-[26,27-3H]-dihydroxyvitamin D3 content in all three isssues. © 1978.

引用

页码：787 / 791

页数：5

共 35 条

[1]

BAELEN HV, 1977, J BIOL CHEM, V252, P2515

[2] VITAMIN-D3 METABOLISM IN IMMATURE JAPANESE QUAIL - EFFECTS OF OVARIAN HORMONES [J].