SYNTHESIS OF 5-(3,4,5-TRIMETHOXYPHENYL)-4-SUBSTITUTED ARYL-3-HYDRAZINOCARBONYLMETHYLTHIO-4H-1,2,4-TRIAZOLES AS POSSIBLE ANTI-INFLAMMATORY AGENTS

被引：23

作者：

JAISWAL, RK ^{[1
]}

PARMAR, SS ^{[1
]}

SINGH, SP ^{[1
]}

BARTHWAL, JP ^{[1
]}

机构：

[1] UNIV N DAKOTA,SCH MED,DEPT PHYSIOL,GRAND FORKS,ND 58202

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1979年 / 16卷 / 03期

关键词：

D O I：

10.1002/jhet.5570160331

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of 5‐(3,4,5‐trimethoxyphenyl)‐4‐substituted aryl‐3‐hydrazinocarbonylmethylthio‐4H‐1,2,4‐triazoles were synthesized and evaluated for their antiprotolytic and antiinflammatory activities. Copyright © 1979 Journal of Heterocyclic Chemistry

引用

页码：561 / 565

页数：5

共 14 条

[1] ANTICONVULSANT ACTIVITY OF 1,2,4-TRIAZOLES [J].

AINSWORTH, C ;

EASTON, NR ;

LIVEZEY, M ;

MORRISON, DE ;

GIBSON, WR .

JOURNAL OF MEDICINAL CHEMISTRY, 1962, 5 (02) :383-&

[2] PROTEASES IN INFLAMMATION [J].

BARNHART, MI ;

QUINTANA, C ;

LENON, HL ;

BLUHM, GB ;

RIDDLE, JM .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1968, 146 (A2) :527-&

[3]

BERTELLI A, 1968, Biochemical Pharmacology, P229

[4] PLETHYSMOMETRIC MEASUREMENT OF SWELLING IN THE FEET OF SMALL LABORATORY ANIMALS [J].

BUTTLE, GAH ;

DARCY, PF ;

HOWARD, EM ;

KELLETT, DN .

NATURE, 1957, 179 (4560) :629-629

[5]

CHAUDHARI A, 1974, RES COMMUN CHEM PATH, V7, P205

[6] SYNTHESIS OF SOME S-TRIAZOLES WITH POTENTIAL ANALGETIC AND ANTIINFLAMMATORY ACTIVITIES [J].

GEORGE, T ;

MEHTA, DV ;

TAHILRAMANI, R ;

DAVID, J ;

TALWALKER, PK .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (04) :335-+

[7]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[8]

Masm C., 1901, J CHEM SOC, V80, P488

[9]

PARMAR SS, 1972, J MED CHEM, V15, P999, DOI 10.1021/jm00279a033

[10] MOLECULAR-BASIS OF SOME NEWER NONSTEROIDAL ANTIINFLAMMATORY AGENTS [J].

PARMAR, SS ;

KISHORE, V ;

ALI, B .

AGENTS AND ACTIONS, 1973, 3 (05) :386-387

← 1 2 →