UNUSUAL LOCATION AND FUNCTION OF THE OPERATOR IN THE ESCHERICHIA-COLI GALACTOSE OPERON

被引：60

作者：

DILAURO, R ^{[1
]}

TANIGUCHI, T ^{[1
]}

MUSSO, R ^{[1
]}

CROMBRUGGHE, BD ^{[1
]}

机构：

[1] NCI,MOLEC BIOL LAB,BETHESDA,MD 20014

来源：

NATURE | 1979年 / 279卷 / 5713期

关键词：

D O I：

10.1038/279494a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The operator of the gal operon is located about 60 base pairs preceding the startpoints of the transcription of the two gal promoters. This location contrasts with the location of the operator in other phage or bacterial operons where the repressor binds more closely to the respective transcription initiation sites. Models explaining how the repressor-operator interactions may control the two gal promoters are presented. © 1979 Nature Publishing Group.

引用

页码：494 / 500

页数：7

共 21 条

[1] GLUCOSE EFFECT AND GALACTOSE ENZYMES OF ESCHERICHIA COLI - CORRELATION BETWEEN GLUCOSE INHIBITION OF INDUCTION AND INDUCER TRANSPORT
ADHYA, S
ECHOLS, H
[J]. JOURNAL OF BACTERIOLOGY, 1966, 92 (03) : 601 - &
[2] MODULATION OF THE 2 PROMOTERS OF THE GALACTOSE OPERON OF ESCHERICHIA-COLI
ADHYA, S
MILLER, W
[J]. NATURE, 1979, 279 (5713) : 492 - 494
[3] NUCLEOTIDE-SEQUENCE OF REGION PRECEDING TRP MESSENGER-RNA INITIATION SITE AND ITS ROLE IN PROMOTER AND OPERATOR FUNCTION
BENNETT, GN
SCHWEINGRUBER, ME
BROWN, KD
SQUIRES, C
YANOFSKY, C
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (07) : 2351 - 2355
[4] SEQUENCE-ANALYSIS OF OPERATOR CONSTITUTIVE MUTANTS OF TRYPTOPHAN OPERON OF ESCHERICHIA-COLI
BENNETT, GN
YANOFSKY, C
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1978, 121 (02) : 179 - 192
[5] CONSTRUCTION AND CHARACTERIZATION OF NEW CLONING VEHICLES .2. MULTIPURPOSE CLONING SYSTEM
BOLIVAR, F
RODRIGUEZ, RL
GREENE, PJ
BETLACH, MC
HEYNEKER, HL
BOYER, HW
CROSA, JH
FALKOW, S
[J]. GENE, 1977, 2 (02) : 95 - 113
[6] MECANISMES REGULATEURS DANS LA BIOSYNTHESE DES ENZYMES DU METABOLISME DU GALACTOSE CHEZ ESCHERICHIA COLI K12 .2. LE DETERMINISME GENETIQUE DE LA REGULATION
BUTTIN, G
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1963, 7 (02) : 183 - &
[7] NUCLEOTIDE-SEQUENCE CHANGES PRODUCED BY MUTATIONS IN LAC PROMOTER OF ESCHERICHIA-COLI
DICKSON, RC
ABELSON, J
JOHNSON, P
REZNIKOFF, WS
BARNES, WM
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1977, 111 (01) : 65 - 75
[8] FEISS M, 1972, GENETICS, V71, P18
[9] NUCLEOTIDE-SEQUENCE OF LAC OPERATOR
GILBERT, W
MAXAM, A
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (12) : 3581 - 3584
[10] SPECIFIC BINDING OF CAP FACTOR TO LAC PROMOTER DNA
MAJORS, J
[J]. NATURE, 1975, 256 (5519) : 672 - 674

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