PRIMARY PULMONARY-HYPERTENSION - RESPONSE TO INDOMETHACIN, TERBUTALINE, AND ISOPROTERENOL

Primary pulmonary hypertension remains a difficult therapeutic problem. Sublingual isoproterenol (Isuprel) was effective in a few cases but the every-2-h dosage schedule is inconvenient on a long-term basis. A case of primary pulmonary hypertension is described in which terbutaline sulfate and indomethacin were tried. There was no sustained response to terbutaline but there seemed to be a response to indomethacin and isoproterenol.