ULTRASTRUCTURAL OBSERVATIONS OF NONSELECTIVE EFFECTS OF RICIN TREATMENT (RCA-120) IN THE RAT DORSAL-ROOT GANGLION

被引：7

作者：

RIVEROMELIAN, C

ARVIDSSON, J

机构：

[1] Department of Anatomy, Karolinska Institutet, Stockholm

来源：

BRAIN RESEARCH | 1990年 / 509卷 / 02期

关键词：

Non-selective degeneration; RCA-120; Spinal ganglion;

D O I：

10.1016/0006-8993(90)90561-O

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The effects of ricin (RCA-120) on non-injected dorsal root ganglion (DRG) cells, sharing the same DRG as the injected ones, were studied after ricin injections into the tibial nerve and B-HRP injections into the peroneal nerve. Numerous DRG cells containing B-HRP reaction product and exhibiting signs of advanced degeneration were observed. The findings suggest that ricin may be released from dying injected DRG neurons and taken up by adjacent non-injected DRG cells, which subsequently degenerate. © 1990.

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页码：335 / 338

页数：4

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