ENDOGENOUS TRANSMEMBRANE TUNNEL FORMATION MEDIATED BY PHI-X174 LYSIS PROTEIN-E

被引：131

作者：

WITTE, A

WANNER, G

BLASI, U

HALFMANN, G

SZOSTAK, M

LUBITZ, W

机构：

[1] UNIV VIENNA,INST MICROBIOL & GENET,ALTHANSTR 14,A-1090 VIENNA,AUSTRIA

[2] UNIV MUNICH,INST BOT,W-8000 MUNICH 19,GERMANY

来源：

JOURNAL OF BACTERIOLOGY | 1990年 / 172卷 / 07期

关键词：

D O I：

10.1128/jb.172.7.4109-4114.1990

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Biochemical and genetic studies have suggested that a transmembrane tunnel structure penetrating the inner and outer membranes is formed during the lytic action of bacteriophage ΦX174 protein E. In this study we directly visualized the lysis tunnel by using high-magnification scanning and transmission electron microscopy.

引用

收藏

页码：4109 / 4114

页数：6

相关论文

共 25 条

[1] SUBCELLULAR-LOCALIZATION OF LETHAL LYSIS PROTEINS OF BACTERIOPHAGES-LAMBDA AND BACTERIOPHAGE-PHI X174 [J].

ALTMAN, E ;

YOUNG, K ;

GARRETT, J ;

ALTMAN, R ;

YOUNG, RY .

JOURNAL OF VIROLOGY, 1985, 53 (03) :1008-1011

[2] OVERLAPPING GENES IN BACTERIOPHAGE-PSIX174 [J].

BARRELL, BG ;

AIR, GM ;

HUTCHISON, CA .

NATURE, 1976, 264 (5581) :34-41

[3] DIFFUSION CONSTANT AND DIMENSION OF BACTERIOPHAGE PHI-X174 AS DETERMINED BY SELF-BEAT LASER LIGHT SPECTROSCOPY AND ELECTRON-MICROSCOPY [J].

BAYER, ME ;

DEBLOIS, RW .

JOURNAL OF VIROLOGY, 1974, 14 (04) :975-980

[4] INFLUENCE OF C-TERMINAL MODIFICATIONS OF PHI-X174 LYSIS GENE-E ON ITS LYSIS-INDUCING PROPERTIES [J].

BLASI, U ;

LUBITZ, W .

JOURNAL OF GENERAL VIROLOGY, 1985, 66 (JUN) :1209-1213

[5]

BLASI U, 1989, J BIOL CHEM, V264, P4552

[6]

BLASI U, 1985, J GEN MICROBIOL, V131, P1107

[7]

BLASI U, 1983, TARGET PENICILLIN, P205

[8]

BLASI U, 1986, BIOL PROPERTIES PEPT, P215

[9] LYTIC ACTIVITY LOCALIZED TO MEMBRANE-SPANNING REGION OF PHI-X174 E PROTEIN [J].

BUCKLEY, KJ ;

HAYASHI, M .

MOLECULAR & GENERAL GENETICS, 1986, 204 (01) :120-125

[10] CONSTRUCTION AND CHARACTERIZATION OF AMPLIFIABLE MULTICOPY DNA CLONING VEHICLES DERIVED FROM P15A CRYPTIC MINIPLASMID [J].

CHANG, ACY ;

COHEN, SN .

JOURNAL OF BACTERIOLOGY, 1978, 134 (03) :1141-1156