ENTRY OF PSEUDORABIES VIRUS INTO CHO CELLS IS BLOCKED AT THE LEVEL OF PENETRATION

被引：11

作者：

SAWITZKY, D

HAMPL, H

HABERMEHL, KO

机构：

[1] FREE UNIV BERLIN, INST CLIN & EXPTL VIROL, HINDENBURGDAMM 27, W-1000 BERLIN 45, GERMANY

[2] ABBOTT DIAGNOST PROD GMBH, WIESBADEN, GERMANY

来源：

ARCHIVES OF VIROLOGY | 1990年 / 115卷 / 3-4期

关键词：

D O I：

10.1007/BF01310539

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Replication of pseudorabies virus (PrV) in Chinese hamster ovary (CHO) cells, a cell line naturally resistant to infection by herpesviruses, is blocked at the level of penetration. Virions bound to the surface of CHO cells are taken up into cytoplasmic vesicles and degraded.

引用

收藏

页码：309 / 316

页数：8

相关论文

共 21 条

[1] CHARACTERIZATION OF A HERPES-SIMPLEX VIRUS TYPE-1 MUTANT WHICH HAS A TEMPERATURE-SENSITIVE DEFECT IN PENETRATION OF CELLS AND ASSEMBLY OF CAPSIDS [J].

ADDISON, C ;

RIXON, FJ ;

PALFREYMAN, JW ;

OHARA, M ;

PRESTON, VG .

VIROLOGY, 1984, 138 (02) :246-259

[2] ENTRY OF HERPES-SIMPLEX VIRUS-1 IN BJ CELLS THAT CONSTITUTIVELY EXPRESS VIRAL GLYCOPROTEIN D IS BY ENDOCYTOSIS AND RESULTS IN DEGRADATION OF THE VIRUS [J].

CAMPADELLIFIUME, G ;

ARSENAKIS, M ;

FARABEGOLI, F ;

ROIZMAN, B .

JOURNAL OF VIROLOGY, 1988, 62 (01) :159-167

[3] ANTI-GLYCOPROTEIN-D ANTIBODIES THAT PERMIT ADSORPTION BUT BLOCK INFECTION BY HERPES-SIMPLEX VIRUS-1 PREVENT VIRION CELL-FUSION AT THE CELL-SURFACE [J].

FULLER, AO ;

SPEAR, PG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (15) :5454-5458

[4] CHARACTERIZATION OF THE ENVELOPE PROTEINS OF PSEUDORABIES VIRUS [J].

HAMPL, H ;

BENPORAT, T ;

EHRLICHER, L ;

HABERMEHL, KO ;

KAPLAN, AS .

JOURNAL OF VIROLOGY, 1984, 52 (02) :583-590

[5]

HAMPL H, 1987, 12TH INT HERP WORKSH, P143

[6] NEUTRALIZING MONOCLONAL-ANTIBODIES SPECIFIC FOR HERPES-SIMPLEX VIRUS GLYCOPROTEIN-D INHIBIT VIRUS PENETRATION [J].

HIGHLANDER, SL ;

SUTHERLAND, SL ;

GAGE, PJ ;

JOHNSON, DC ;

LEVINE, M ;

GLORIOSO, JC .

JOURNAL OF VIROLOGY, 1987, 61 (11) :3356-3364

[7] HERPES-SIMPLEX VIRUSES LACKING GLYCOPROTEIN-D ARE UNABLE TO INHIBIT VIRUS PENETRATION - QUANTITATIVE EVIDENCE FOR VIRUS-SPECIFIC CELL-SURFACE RECEPTORS [J].

JOHNSON, DC ;

LIGAS, MW .

JOURNAL OF VIROLOGY, 1988, 62 (12) :4605-4612

[8] HERPES-SIMPLEX VIRUS GLYCOPROTEIN-D MEDIATES INTERFERENCE WITH HERPES-SIMPLEX VIRUS-INFECTION [J].

JOHNSON, RM ;

SPEAR, PG .

JOURNAL OF VIROLOGY, 1989, 63 (02) :819-827

[9] A HERPES-SIMPLEX VIRUS MUTANT IN WHICH GLYCOPROTEIN-D SEQUENCES ARE REPLACED BY BETA-GALACTOSIDASE SEQUENCES BINDS TO BUT IS UNABLE TO PENETRATE INTO CELLS [J].

LIGAS, MW ;

JOHNSON, DC .

JOURNAL OF VIROLOGY, 1988, 62 (05) :1486-1494

[10] A VIRION-ASSOCIATED GLYCOPROTEIN ESSENTIAL FOR INFECTIVITY OF HERPES-SIMPLEX VIRUS TYPE-1 [J].

LITTLE, SP ;

JOFRE, JT ;

COURTNEY, RJ ;

SCHAFFER, PA .

VIROLOGY, 1981, 115 (01) :149-160