2-STEP SYNTHESIS OF SUBSTITUTED INDOLO[1,2-A]-QUINOXALIN-6-ONES

被引：20

作者：

BEACH, MJ ^{[1
]}

HOPE, R ^{[1
]}

KLAUBERT, DH ^{[1
]}

RUSSELL, RK ^{[1
]}

机构：

[1] RW JOHNSON PHARMACEUT RES INST,RARITAN,NJ 08869

来源：

SYNTHETIC COMMUNICATIONS | 1995年 / 25卷 / 14期

关键词：

D O I：

10.1080/00397919508015898

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of indole-2-carboxylates with 2-fluoronitrobenzenes in 1-methyl-2-pyrrolidinone containing NaH affords the 1-(2-nitrophenyl)indole-2-carboxlyates 1. These compounds are reduced with iron in acetic acid to afford the indolo[1,2-a]quinoxalin-6(5H)-ones 2.

引用

页码：2165 / 2183

页数：19

共 16 条

[1] ON THE CONVERGENCE OF ITERATIVE COMPUTATION IN THE LAOCOON-3 PROGRAM
ATTIMONELLI, M
SCIACOVELLI, O
[J]. ORGANIC MAGNETIC RESONANCE, 1980, 13 (04): : 277 - 278
[2] COPPER CATALYZED PHENYLATION OF INDOLES BY TRIPHENYLBISMUTH BIS-TRIFLUOROACETATE
BARTON, DHR
FINET, JP
KHAMSI, J
[J]. TETRAHEDRON LETTERS, 1988, 29 (10) : 1115 - 1118
[3] THROMBOXANE RECEPTOR ANTAGONISM COMBINED WITH THROMBOXANE SYNTHASE INHIBITION .8. N-ALKYLATION OF INDOLE RING USING MITSUNOBU REACTION
BHAGWAT, SS
GUDE, C
[J]. TETRAHEDRON LETTERS, 1994, 35 (12) : 1847 - 1850
[4] BOURAK M, 1990, HETEROCYCLES, V31, P447
[5] ANALYSIS OF NMR SPECTRA BY LEAST SQUARES
CASTELLANO, S
BOTHNERB.AA
[J]. JOURNAL OF CHEMICAL PHYSICS, 1964, 41 (12) : 3863 - +
[6] FANTA PE, 1974, SYNTHESIS-STUTTGART, V1, P9
[7] COMPUTER ANALYSIS OF NMR SPECTRA - MAGNETIC EQUIVALENCE FACTORING
FERGUSON, RC
MARQUARDT, DW
[J]. JOURNAL OF CHEMICAL PHYSICS, 1964, 41 (07) : 2087 - &
[8] GOSHAEV M, 1972, USP KHIM+, V41, P2198
[9] HENDI SB, 1981, INDIAN J CHEM B, V20, P330
[10] KHAN MA, 1970, REC CHEM PROG, V31, P43

← 1 2 →