COGNITIVE DECLINE IN AN ELDERLY POPULATION - A 2 WAVE STUDY OF CHANGE

被引:98
作者
BRAYNE, C
GILL, C
PAYKEL, ES
HUPPERT, F
OCONNOR, DW
机构
[1] UNIV CAMBRIDGE,INST PUBL HLTH,DEPT PSYCHIAT,CAMBRIDGE CB2 2SR,ENGLAND
[2] UNIV CAMBRIDGE,INST PUBL HLTH,MRC,BIOSTAT UNIT,CAMBRIDGE CB2 2SR,ENGLAND
[3] MONASH UNIV,DEPT PSYCHOGERIATR,MELBOURNE,VIC 3004,AUSTRALIA
基金
英国医学研究理事会;
关键词
D O I
10.1017/S0033291700034930
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
A sample of 1111 survivors from a population aged 75 years and over completed the Mini-Mental State Examination (MMSE) twice, separated by 28 months on average. There was a mean decline of 1.3 points in MMSE score. With increasing age, mean drop in score also increased. The proportion at each age identified as newly cognitively impaired according to any standard cutpoint on MMSE rose markedly. Mean decline was greater in women than men even after adjustment for age. Cognitive change on the MMSE was approximately unimodally and normally distributed. This distribution was a marked contrast to the distribution of MMSE scores themselves, which was skewed due to truncation of scores at the maximum. The decline was not due to the inclusion of individuals with physical impairment. These findings indicate that cognitive decline, like dementia, becomes increasingly common with advancing age, and suggest that dementia may be regarded as one extreme of the continuum of cognitive decline.
引用
收藏
页码:673 / 683
页数:11
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