65ZN AND 69MZN STUDIES IN DOG MONKEY AND MAN - PROSTATIC SCINTISCANNING

被引:20
作者
JOHNSTON, GS
WADE, JC
MURPHY, GP
SCOTT, WW
机构
[1] Radioisotope Section, Urology Service, Walter Reed General Hospital, Washington, DC
[2] The James Buchanan Brady Urological Institute, The Johns Hopkins Hospital, Baltimore, MD
关键词
D O I
10.1016/0022-4804(68)90003-6
中图分类号
R61 [外科手术学];
学科分类号
摘要
65Zn chloride and 69mZn chloride and citrate have been studied in a total of 34 dogs, 2 rhesus monkeys, and 10 men. Timed concentrations were measured in the blood of all and in the bile, urine, and fresh tissues of 32 dogs and 2 monkeys. In addition, the influence of castration, timing, testosterone proprionate treatment, pilocarpine administration, and other combinations of these factors were studied. We have shown that significant prostatic concentrations of radioactive zinc were obtainable in the dog, in the monkey, and in man. In vitro scans of the dog prostate were obtained using 65Zn chloride. Both in vivo and in vitro, clinical human prostatic scans were performed using 69mZn chloride. © 1968.
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页码:528 / &
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