LITHOSPERMOSIDE AND DASYCARPONIN, CYANOGLUCOSIDES FROM THALICTRUM

被引：23

作者：

WU, J

FAIRCHILD, EH

BEAL, JL

TOMIMATSU, T

DOSKOTCH, RW

机构：

[1] Division of Pharmacognosy and Natural Products Chemistry, College of Pharmacy, Ohio State University, Columbus

来源：

JOURNAL OF NATURAL PRODUCTS | 1979年 / 42卷 / 05期

关键词：

D O I：

10.1021/np50005a011

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two cyanoglucosides from Thalictrum are assigned structures by physical and chemical methods. The glycoside from T. rugosum and T. revolutum is identical with lithospermoside and griffonin. Its absolute stereochemistry was determined as in 1 from circular dichroism studies with the dibenzoate of the modified aglycone, griff onilide (2). The other glycoside, dasycarponin (5), from T. dasycarpum is the 4-epimer of lithospermoside. Proton and carbon nuclear magnetic resonances, circular dichroism and other spectral data are given for these compounds and their products. © 1979, American Chemical Society. All rights reserved.

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页码：500 / 511

页数：12

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