DETECTION OF FEMTOMOLE AND SUB-FEMTOMOLE LEVELS OF PEPTIDES BY TANDEM MAGNETIC-SECTOR REFLECTRON TIME-OF-FLIGHT MASS-SPECTROMETRY AND MATRIX-ASSISTED LASER DESORPTION IONIZATION

被引：52

作者：

STROBEL, FH ^{[1
]}

SOLOUKI, T ^{[1
]}

WHITE, MA ^{[1
]}

RUSSELL, DH ^{[1
]}

机构：

[1] TEXAS A&M UNIV SYST, DEPT CHEM, COLLEGE STN, TX 77843 USA

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 1991年 / 2卷 / 01期

关键词：

D O I：

10.1016/1044-0305(91)80066-G

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This article describes results of low-level (sub-femtomole) detection of peptides by matrix-assisted laser desorption ionization. The matrix-assisted laser desorption ionization method can be used for low-level detection of the parent ion, either [M + H]+ or [M + Na]+, and collision-induced dissociation of the parent ion can be performed at the picomole level. The instrument used for these studies is a novel high-performance magnetic sector (electric(E)/magnetic(B) sector) /reflectron time-of-flight (TOF) tandem mass spectrometer (EB/TOF).

引用

页码：91 / 94

页数：4

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