ASYMMETRIC-SYNTHESIS OF MACBECIN-I

被引：50

作者：

EVANS, DA

MILLER, SJ

ENNIS, MD

ORNSTEIN, PL

机构：

[1] Department of Chemistry, Harvard University, Cambridge

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 04期

关键词：

D O I：

10.1021/jo00030a006

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The asymmetric synthesis of macbecin I is described wherein the absolute stereochemical relationships were established through the use of chiral boron aldol bond constructions and internally directed alpha-methoxy ketone reduction, while the E,Z dienic amide moiety was installed in one step using a vinylogous phosphonate reagent.

引用

页码：1067 / 1069

页数：3

共 32 条

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