METHYLGLYOXAL AND CELL VIABILITY

被引：8

作者：

BRAUN, L ^{[1
]}

GARZO, T ^{[1
]}

RIBA, P ^{[1
]}

MANDL, J ^{[1
]}

KALAPOS, MP ^{[1
]}

机构：

[1] SEMMELWEIS UNIV MED,SCH MED,INST BIOCHEM 1,BUDAPEST,HUNGARY

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1994年 / 26卷 / 08期

关键词：

D O I：

10.1016/0020-711X(94)90069-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. Methylglyoxal by depleting glutathione stores increased Trypan-blue uptake by the cells incubated in glucose, pyruvate and amino acids free medium. 2. Only a transient fall of glutathione concentration without any effect on cell viability was caused by methylglyoxal when the medium was supplemented with above-mentioned compounds. 3. The role of gamma-glutamyl-transpeptidase is discussed.

引用

页码：987 / 990

页数：4

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