IMMUNOLOGICAL STUDIES ON SIMIAN MALARIA .3. IMMUNITY TO CHALLENGE AND ANTIGENIC VARIATION IN P KNOWLESI

被引：32

作者：

VOLLER, A

ROSSAN, RN

机构：

[1] Nuffield Institute of Comparative Medicine, The Zoological Society of London, London, N.W.1, Regent's Park

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1969年 / 63卷 / 04期

关键词：

D O I：

10.1016/0035-9203(69)90040-6

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Immunity to reinfection in the simian malaria system studied was evidenced by (a) a delay in development of infections, (b) a milder course of parasitaemia, or (c) complete resistance to challenge. The immunity produced by repeated exposure to one antigenic variant was effective against subsequent challenge with heterologous variants. Populations of parasites isolated from different recrudescences of chronic P. knowlesi infections were shown to be antigenically distinct. © 1969 Royal Society of Tropical Medicine and Hygiene.

引用

页码：507 / +

页数：1

共 17 条

[1]

BRAY R S, 1962, Riv Malariol, V41, P199

[2]

BROWN IN, 1968, IMMUNOLOGY, V14, P127

[3] IMMUNITY TO MALARIA - ANTIGENIC VARIATION IN CHRONIC INFECTIONS OF PLASMODIUM KNOWLESI [J].