TENOTOMY-INDUCED MOTOR END-PLATE ALTERATIONS IN RAT SOLEUS MUSCLE

被引：19

作者：

PACHTER, BR

SPIELHOLZ, NI

机构：

[1] Department of Rehabilitation Medicine, New York University Medical Center, New York, New York

来源：

ANATOMICAL RECORD | 1990年 / 228卷 / 01期

关键词：

D O I：

10.1002/ar.1092280114

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The effects of tenotomy on the ultrastructure of rat soleus muscle motor endplates were examined both qualitatively and quantitatively. Rat soleus muscle was studied 2 weeks following tenotomy and compared with normal littermates. The motor endplates from the tenotomized muscles were found to exhibit both degenerative and regenerative changes. Degeneration consisted of postjunctional fold breakdown, exposed junctional folds, myelin‐like bodies within the subjunctional sarcoplasm, and dense bodies within the Schwann cell cytoplasm. The regenerative changes consisted of several small nerve terminals occurring within the same primary synaptic cleft and several axons wrapped by the same Schwann cell. The results demonstrate that tenotomy induces denervation‐like changes at endplates that lead to terminal sprouting within the neuromuscular junctional area and remodelling. Copyright © 1990 Wiley‐Liss, Inc.

引用

页码：104 / 108

页数：5

共 18 条

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