CRYSTALLIZATION AND PRELIMINARY CRYSTALLOGRAPHIC ANALYSIS OF A TETRAMERIC ISOLECTIN FROM VICIA-VILLOSA, SPECIFIC FOR THE TN ANTIGEN

被引：7

作者：

EISELE, JL

TELLO, D

OSINAGA, E

ROSETO, A

ALZARI, PM

机构：

[1] INST PASTEUR, UNITE NEUROBIOL MOLEC, CNRS, URA 1284, F-75724 PARIS, FRANCE

[2] UNIV TECHNOL COMPIEGNE, DIV IMMUNOCYTOL APPL, CNRS, URA 1442, F-60206 COMPIEGNE, FRANCE

[3] INST PASTEUR, UNITE IMMUNOL STRUCT, CNRS, URA 359, F-75724 PARIS, FRANCE

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1993年 / 230卷 / 02期

关键词：

PLANT LECTIN; TN ANTIGEN; X-RAY CRYSTALLOGRAPHY; VICIA-VILLOSA; CRYSTALLIZATION;

D O I：

10.1006/jmbi.1993.1180

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Isolectin B4 isolated from Vicia villosa seeds is specific for the Tn antigen, a carcinoma-associated molecular marker. Crystals of the isolectin grown in the presence of carbohydrate are tetragonal, space group P41 (or P43), with a = 91.3 Å, c = 151.7 Å and one tetramer in the asymmetric unit. The crystals diffract X-rays to 2.8 Å resolution and are suitable for high-resolution structural analysis. © 1993 Academic Press Limited.

引用

页码：670 / 672

页数：3

共 19 条

[1] PRELIMINARY CRYSTALLOGRAPHIC STUDY OF THE ALPHA-D-GALACTOSE-SPECIFIC LECTIN FROM JACK FRUIT (ARTOCARPUS-INTEGRA) SEEDS [J].