EVIDENCE FOR DIRECT HYDROGEN TRANSFER DURING GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE CATALYSIS

被引：10

作者：

ALLISON, WS

CONNORS, MJ

PARKER, DJ

机构：

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1969年 / 34卷 / 04期

关键词：

D O I：

10.1016/0006-291X(69)90410-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An irreversible one-turnover reaction between 1-3H-glyceraldehyde-3-phosphate and the lobster muscle glyceraldehyde-3-phosphate dehydrogenase (TPD) coenzyme complex has been carried out. Analysis of the products of this reaction has shown that DPN3H is formed and tritium is not incorporated into the enzyme. These results suggest that hydrogen is transferred directly from the reduced substrate to the coenzyme during TPD catalysis. © 1969.

引用

页码：503 / &

共 8 条

[1]

ALLISON WS, 1964, J BIOL CHEM, V239, P2140

[2]

CHAN TL, 1968, J BIOL CHEM, V243, P6284

[3] AMINO-ACID SEQUENCE OF GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE FROM LOBSTER MUSCLE [J].