CLONING AND NUCLEOTIDE-SEQUENCE OF CDNA-ENCODING HUMAN ERYTHROCYTE BAND-7 INTEGRAL MEMBRANE-PROTEIN

被引:76
作者
HIEBLDIRSCHMIED, CM
ENTLER, B
GLOTZMANN, C
MAURERFOGY, I
STRATOWA, C
PROHASKA, R
机构
[1] UNIV VIENNA,INST BIOCHEM,WUHRINGER STR 17,A-1090 VIENNA,AUSTRIA
[2] ERNST BOEHRINGER INST ARZNEIMITTELFORSCH,VIENNA,AUSTRIA
基金
奥地利科学基金会;
关键词
ERYTHROCYTE; MEMBRANE PROTEIN; BAND-7; CDNA SEQUENCE; PROTEIN STRUCTURE ANALYSIS;
D O I
10.1016/0167-4781(91)90047-P
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
cDNA clones encoding the human erythrocyte band 7 membrane protein were isolated by immunoscreening from bone marrow and HeLa cell lambda-gt11 cDNA libraries, and their nucleotide sequences were determined. HeLa- and bone marrow cell-derived sequences were identical, except for one nucleotide; the deduced sequence of 287 amino acids was confirmed by sequence identity with peptides of the erythroid protein. Structure analysis assigned band 7 protein to the type lb transmembrane proteins.
引用
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页码:123 / 124
页数:2
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