INHIBITION OF BACTERIAL ADHERENCE BY NASOPHARYNGEAL SECRETIONS

被引：38

作者：

KURONO, Y ^{[1
]}

SHIGEMI, H ^{[1
]}

SHIMAMURA, K ^{[1
]}

MOGI, G ^{[1
]}

机构：

[1] MED COLL OITA,DEPT OTOLARYNGOL,1-1 IDAIGAOKA,HAZAMA,OITA 87956,JAPAN

来源：

ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY | 1991年 / 100卷 / 06期

关键词：

BACTERIAL ADHERENCE; HAEMOPHILUS-INFLUENZAE; NASOPHARYNX; SECRETORY IGA; STREPTOCOCCUS-PNEUMONIAE;

D O I：

10.1177/000348949110000605

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The role of secretory immunoglobulin (Ig) A in nasopharyngeal secretions in the adherence of Streptococcus pneumoniae and Hemophilus influenzae to nasopharyngeal epithelial cells was investigated in vitro. The adherence was remarkably reduced by treating bacteria with nasopharyngeal secretions, and the antiadhesive activity was significantly greater in nasopharyngeal secretions having secretory IgA antibody activity against bacteria than in those having no activity. Noticeable changes were not observed in the antiadhesive activity caused by absorption of IgG from nasopharyngeal secretions. Results suggest that secretory IgA in nasopharyngeal secretions is related to bacterial adherence and adds to the prevention of nasopharyngeal infections.

引用

页码：455 / 458

页数：4

共 12 条

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