GAMMA-GLUTAMYL-TRANSFERASE TRANSPEPTIDASE OF HUMAN AMNIOTIC-FLUID

被引：13

作者：

PALEKAR, AG

MADDAIAH, VT

COLLIPP, PJ

MACRI, JN

机构：

[1] NASSAU CTY MED CTR, DEPT PEDIAT, E MEADOW, NY 11554 USA

[2] SUNY STONY BROOK, STONY BROOK HLTH SCI CTR, DEPT OBSTET & GYNECOL, STONY BROOK, NY 11794 USA

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1981年 / 141卷 / 07期

关键词：

D O I：

10.1016/0002-9378(81)90705-5

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

.gamma.-Glutamyl transpeptidase (GGTP) activity in normal amniotic fluids and corresponding maternal sera obtained at various gestational periods was measured. The ontogenic pattern of enzyme activity in amniotic fluid is very similar to .alpha.-fetoprotein (AFP). The levels of these 2 proteins behaved differently in corresponding maternal sera. In amniotic fluids obtained from pregnancies with neural tube defects (NTD), only AFP concentration was abnormally high, whereas GGTP activity was normal.

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页码：788 / 791

页数：4

相关论文

共 16 条

[1] PRENATAL DIAGNOSIS - CHEMICAL METHODS [J].

BROCK, DJH .

BRITISH MEDICAL BULLETIN, 1976, 32 (01) :16-20

[2] ACTIVATION BY CHEMICAL CARCINOGENS OF GAMMA-GLUTAMYL TRANSPEPTIDASE IN RAT AND MOUSE LIVER [J].

FIALA, S ;

FIALA, ES .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1973, 51 (01) :151-158

[3]

KOTTGEN E, 1976, BIOCHEM BIOPH RES CO, V72, P61

[4]

KOTTGEN E, 1976, H-S Z PHYSIOL CHEM, V357, P1439

[5] GLUTATHIONE AND RELATED GAMMA-GLUTAMYL COMPOUNDS - BIOSYNTHESIS AND UTILIZATION [J].

MEISTER, A ;

TATE, SS .

ANNUAL REVIEW OF BIOCHEMISTRY, 1976, 45 :559-604

[6]

NORGAARDPEDERSE.B, 1976, SCAND J IMMUNOL S4, V5

[7] GAMMA-GLUTAMYL CYCLE - A POSSIBLE TRANSPORT SYSTEM FOR AMINO ACIDS [J].

ORLOWSKI, M ;

MEISTER, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1970, 67 (03) :1248-&

[8] DEVELOPMENTAL-CHANGES IN CARBOHYDRATE MOIETY OF HUMAN ALPHA-FETOPROTEIN [J].

RUOSLAHTI, E ;

ENGVALL, E ;

PEKKALA, A ;

SEPPALA, M .

INTERNATIONAL JOURNAL OF CANCER, 1978, 22 (05) :515-520

[9] STUDIES OF CARCINO-FETAL PROTEINS - PHYSICAL AND CHEMICAL PROPERTIES OF HUMAN ALPHA-FETOPROTEIN [J].

RUOSLAHTI, E ;

SEPPALA, M .

INTERNATIONAL JOURNAL OF CANCER, 1971, 7 (02) :218-+

[10] REACTIVITY OF AMNIOTIC-FLUID ALPHA-FETOPROTEIN WITH CONCANAVALIN-A IN DIAGNOSIS OF NEURAL TUBE DEFECTS [J].

SMITH, CJ ;

KELLEHER, PC ;

BELANGER, L ;

DALLAIRE, L .

BMJ-BRITISH MEDICAL JOURNAL, 1979, 1 (6168) :920-921