CHEMISTRY OF THE CYTOTOXIC PRINCIPLES OF THE MARINE FUNGUS LIGNINCOLA-LAEVIS

被引：11

作者：

ABRAHAM, SP ^{[1
]}

HOANG, TD ^{[1
]}

ALAM, M ^{[1
]}

JONES, EBG ^{[1
]}

机构：

[1] UNIV PORTSMOUTH,SCH BIOL SCI,PORTSMOUTH,ENGLAND

来源：

PURE AND APPLIED CHEMISTRY | 1994年 / 66卷 / 10-11期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1351/pac199466102391

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A methylene chloride: methanol (2:1v/v) extract of the marine fungus Lignincol laevis was found to inhibit the growth of mouse murine leukemia cells (L 1210). Large scale culturing followed by fractionation of the extract on silica gel has resulted in the isolation of a cytotoxic 1 along with 7-hydroxyergosterol 2 and a ceramide 3. Structures of the isolated compounds were established with the help of two-dimensional NMR spectroscopy.

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页码：2391 / 2394

页数：4

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