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GLUCOSE TRANSPORTER EXPRESSION IN RAT MAMMARY-GLAND

被引：62
作者：
BURNOL, AF
LETURQUE, A
LOIZEAU, M
POSTIC, C
GIRARD, J
机构：
[1] Ctr Recherche sur la Nutrition, CNRS, 92190 Meudon
来源：
BIOCHEMICAL JOURNAL | 1990年 / 270卷 / 01期
关键词：
D O I：
10.1042/bj2700277
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The expression of different glucose transporter isoforms was measured during the development and differentiation of the rat mammary gland. Before conception, when the mammary gland is mainly composed of adipocytes, Glut 4 and Glut 1 mRNAs and proteins were present. During pregnancy, the expression of Glut 4 decreased progressively, whereas that of Glut 1 increased. In the lactating mammary gland only Glut 1 was present, and was expressed at a high level. The absence of Glut 4 suggests that glucose transport is not regulated by insulin in the lactating rat mammary gland.
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页码：277 / 279
页数：3
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