PREVENTION OF UNNECESSARY PREGNANCY TERMINATIONS BY COUNSELING WOMEN ON DRUG, CHEMICAL, AND RADIATION EXPOSURE DURING THE 1ST TRIMESTER

被引:67
作者
KOREN, G
PASTUSZAK, A
机构
[1] HOSP SICK CHILDREN,DEPT PEDIAT,DIV CLIN PHARMACOL,TORONTO M5G 1X8,ONTARIO,CANADA
[2] HOSP SICK CHILDREN,RES INST,TORONTO M5G 1X8,ONTARIO,CANADA
[3] UNIV TORONTO,DEPT PEDIAT,TORONTO M5G 1X8,ONTARIO,CANADA
[4] UNIV TORONTO,DEPT PHARMACOL,TORONTO M5G 1X8,ONTARIO,CANADA
关键词
D O I
10.1002/tera.1420410602
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
As part of a new approach to counselling pregnant women concerned about antenatal exposure to drugs, chemicals, or radiation, we measured their tendency to terminate their pregnancy by using a visual analogue scale (VAS). Analysis of 78 cases where women had less than 50% tendency to continue pregnancy before they were advised by us reveals that 61 decided to continue their pregnancy after the consultation (57 normal, healthy infants, four miscarriages) and 17 terminated. Women who continued their pregnancy significantly changed their tendency after we discussed relevant information with them (from 34.3 ± 2.5% to 84.5 ± 3.3%, P<0.00001), whereas most of those who eventually terminated pregnancy did not change their tendency to continue pregnancy beyond the 50% mark (from 24.8 ± 5.4% to 45.1 ± 9.8%) (P>0.1). Only two of the women who terminated their pregnancy were exposed to teratogenic drugs; however, in most other cases, other obvious reasons, unrelated to the exposure in question, were identified by the women as leading reasons for termination. An appropriate intervention in early pregnancy can prevent unnecessary pregnancy terminations by correcting misinformation and thereby decreasing the unrealistically high perception of risk by women exposed to nonteratogens. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company
引用
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页码:657 / 661
页数:5
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