ENDOGENOUS TRANSMEMBRANE ELECTRICAL GRADIENTS ASSOCIATED WITH HUMAN PLACENTAL MICROVILLOUS MEMBRANE-VESICLES

被引：2

作者：

SHENNAN, DB

REID, D

机构：

来源：

EXPERIMENTAL PHYSIOLOGY | 1991年 / 76卷 / 02期

关键词：

D O I：

10.1113/expphysiol.1991.sp003494

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Experiments were designed to test for the presence of an endogenous (i.e. Donnan) electrical potential in human placental microvillous membrane vesicles. Vesicles were capable of passively accumlating K+ (Rb-86+) above unity in a manner which was influenced by both pH and ionic strength of the medium. It appears that the transmembrane electrical potential is generated by the presence of fixed negative charges associated with the vesicle interior.

引用

页码：277 / 280

页数：4

共 7 条

[1] L-PROLINE TRANSPORT BY BRUSH-BORDER MEMBRANE-VESICLES PREPARED FROM HUMAN-PLACENTA [J].

BOYD, CAR ;

LUND, EK .

JOURNAL OF PHYSIOLOGY-LONDON, 1981, 315 (JUN) :9-19

[2] USE OF ION-EXCHANGE RESINS FOR STUDYING ION-TRANSPORT IN BIOLOGICAL-SYSTEMS [J].

GASKO, OD ;

KNOWLES, AF ;

SHERTZER, HG ;

SUOLINNA, EM ;

RACKER, E .

ANALYTICAL BIOCHEMISTRY, 1976, 72 (1-2) :57-65

[3] DONNAN EQUILIBRIUM AND PH GRADIENT IN ISOLATED TRACHEAL APICAL MEMBRANE-VESICLES [J].

LANGRIDGESMITH, JE ;

DUBINSKY, WP .

AMERICAN JOURNAL OF PHYSIOLOGY, 1985, 249 (05) :C417-C420

[4] RELATIONSHIP OF THE DONNAN POTENTIAL TO THE TRANSMEMBRANE PH GRADIENT IN TRACHEAL APICAL MEMBRANE-VESICLES [J].

LANGRIDGESMITH, JE ;

DUBINSKY, WP .

JOURNAL OF MEMBRANE BIOLOGY, 1986, 94 (03) :197-204

[5] MECHANISM OF CL- TRANSLOCATION ACROSS SMALL INTESTINAL BRUSH-BORDER MEMBRANE .1. ABSENCE OF NA+-CL- COTRANSPORT [J].

LIEDTKE, CM ;

HOPFER, U .

AMERICAN JOURNAL OF PHYSIOLOGY, 1982, 242 (03) :G263-G271

[6]

MURPHY CT, 1987, J PHYSIOL-LONDON, V386, pP110

[7] CHLORIDE TRANSPORT IN HUMAN PLACENTAL MICROVILLUS MEMBRANE-VESICLES .1. EVIDENCE FOR ANION-EXCHANGE [J].

SHENNAN, DB ;

DAVIS, B ;

BOYD, CAR .

PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 1986, 406 (01) :60-64

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