A NOVEL BIOACTIVE SESTERTERPENE BASED ON AN UNPRECEDENTED TRICYCLIC SKELETON FROM THE CARIBBEAN SPONGE CACOSPONGIA CF LINTEIFORMIS

被引：20

作者：

FATTORUSSO, E ^{[1
]}

LANZOTTI, V ^{[1
]}

MAGNO, S ^{[1
]}

MAYOL, L ^{[1
]}

PANSINI, M ^{[1
]}

机构：

[1] IST ZOOL,I-16126 GENOA,ITALY

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 25期

关键词：

D O I：

10.1021/jo00051a045

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel sesterterpene, lintenone (1), with an unprecedented tricyclic skeleton was isolated from the caribbean sponge Cacospongia cf. linteiformis. The structure of lintenone was assigned on the basis of extensive spectral studies, including H-1-H-1 (COSY and HOHAHA) and H-1-C-13 (XHCORR and COLOC) 2D NMR experiments. Compound 1 was found to possess high ichthyotoxicity and antifeedant properties. It is also moderately toxic against brine shrimp.

引用

页码：6921 / 6924

页数：4

共 23 条

[1] MLEV-17-BASED TWO-DIMENSIONAL HOMONUCLEAR MAGNETIZATION TRANSFER SPECTROSCOPY [J].