MERSACIDIN, A NEW ANTIBIOTIC FROM BACILLUS FERMENTATION, ISOLATION, PURIFICATION AND CHEMICAL CHARACTERIZATION

被引：99

作者：

CHATTERJEE, S ^{[1
]}

LAD, SJ ^{[1
]}

PHANSALKAR, MS ^{[1
]}

RUPP, RH ^{[1
]}

GANGULI, BN ^{[1
]}

FEHLHABER, HW ^{[1
]}

KOGLER, H ^{[1
]}

机构：

[1] HOECHST AG,PHARMA RES,W-6230 FRANKFURT 80,GERMANY

来源：

JOURNAL OF ANTIBIOTICS | 1992年 / 45卷 / 06期

关键词：

D O I：

10.7164/antibiotics.45.832

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Mersacidin (1) is a new peptide antibiotic containing beta-methyllanthionine. It is classified as a member of the proposed lantibiotic group of antibiotics, and is produced by a species of Bacillus. Mersacidin has a molecular weight of 1,824 (C80H120N20O21S4). The antibiotic is active against Gram-positive organisms including methicillin-resistant Staphylococcus aureus, but has no activity against Gram-negative bacteria or fungi.

引用

页码：832 / 838

页数：7

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