LOCAL EXTRAGONADAL ROLES OF ACTIVINS

被引：42

作者：

BILEZIKJIAN, LM

VALE, WW

机构：

[1] Clayton Foundation Laboratories for Peptide Biology, The Salk Institute, La Jolla

来源：

TRENDS IN ENDOCRINOLOGY AND METABOLISM | 1992年 / 3卷 / 06期

关键词：

D O I：

10.1016/1043-2760(92)90031-U

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Activins were initially isolated from gonadal fluids based on their ability to stimulate FSH secretion from gonadotropes of the anterior pituitary. They represent a group of homo/heterodimeric proteins that are structurally related to the transforming growth factor-beta superfamily of growth and differentiation factors. The importance of activins as autocrine and paracrine modulators of a diverse set of biologic functions is now appreciated based on their widespread anatomic distribution and numerous biologic activities.

引用

页码：218 / 223

页数：6

共 68 条

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