NONSPECIFIC RESISTANCE OF SERRATIA-MARCESCENS AGAINST ANTI-MICROBIAL DRUGS - RESISTANCE OR DECREASED SUSCEPTIBILITY OF PHENOTYPIC VARIANTS AGAINST CHLORAMPHENICOL, NALIDIXIC-ACID, NITROFURANTOIN, SULFONAMIDES AND TRIMETHOPRIM

被引：8

作者：

TRAUB, WH ^{[1
]}

FUKUSHIMA, PI ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT LAB MED,SAN FRANCISCO,CA 94143

来源：

CHEMOTHERAPY | 1979年 / 25卷 / 04期

关键词：

Chloramphenicol; Nalidixic acid; Nitrofurantoin; Nonspecific; Resistance; Resistance plasmids; Serratia marcescens; Sulfonamides; Trimethoprim;

D O I：

10.1159/000237840

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Several clinical isolates and O-antigen reference strains of Serratia marcescens were shown to yield spontaneously phenotypic variants with nonspecific, combined resistance or decreased susceptibility for chloramphenicol, nalidixic acid, nitrofurantoin, sulfonamides, and trimethoprim, including cotrimoxazole. Additional presumptive evidence indicated that this resistance phenomenon is not mediated extrachromosomally, but rather chromosomally. The nature of this novel resistance mechanism remains to be elucidated. © 1979 S. Karger AG, Basel.

引用

页码：196 / 203

页数：8

共 10 条

[1]

BAUER AW, 1966, AM J CLIN PATHOL, V45, P493

[2]

Edwards PR., 1972, IDENTIFICATION ENTER

[3] SIMPLE AGAROSE-GEL ELECTROPHORETIC METHOD FOR IDENTIFICATION AND CHARACTERIZATION OF PLASMID DEOXYRIBONUCLEIC-ACID [J].

MEYERS, JA ;

SANCHEZ, D ;

ELWELL, LP ;

FALKOW, S .

JOURNAL OF BACTERIOLOGY, 1976, 127 (03) :1529-1537

[4] MUTANTS OF KLEBSIELLA-PNEUMONIAE RESISTANT TO SEVERAL ANTIBIOTICS [J].

SMITH, HW .

NATURE, 1976, 259 (5541) :307-308

[5]

STEERS EDWARD, 1959, ANTIBIOT AND CHEMOTHER, V9, P307

[6] BACTERIOCIN (MARCESCIN) TYPING OF CLINICAL ISOLATES OF SERRATIA-MARCESCENS [J].

TRAUB, WH ;

RAYMOND, EA ;

STARTSMAN, TS .

APPLIED MICROBIOLOGY, 1971, 21 (05) :837-+

[7]

TRAUB WH, 1976, ZBL BAKT-INT J MED M, V234, P528

[8] CHARACTERIZATION OF A NOSOCOMIALLY SIGNIFICANT, MULTIPLE DRUG-RESISTANT STRAIN OF SERRATIA-MARCESCENS [J].

TRAUB, WH ;

KLEBER, I ;

PUHLER, A ;

BURKARDT, HJ .

CHEMOTHERAPY, 1976, 22 (05) :297-312

[9] SELECTED AND SPONTANEOUS VARIANTS OF SERRATIA-MARCESCENS WITH COMBINED RESISTANCE AGAINST CHLORAMPHENICOL, NALIDIXIC-ACID, AND TRIMETHOPRIM [J].

TRAUB, WH ;

KLEBER, I .

CHEMOTHERAPY, 1977, 23 (06) :436-451

[10] SUSCEPTIBILITY OF PSEUDOMONAS-AERUGINOSA TO CARBENICILLIN [J].

TRAUB, WH ;

RAYMOND, EA .

APPLIED MICROBIOLOGY, 1970, 20 (04) :630-&

← 1 →