INFLUENCE OF HYPERBARIC OXYGENATION ON BILIRUBIN AND DITAUROBILIRUBIN AUTOXIDATION AND PORPHYRIN-SENSITIZED PHOTOOXIDATION

被引：6

作者：

JIRSA, M

SIP, M

JIRSA, M

机构：

[1] CHARLES UNIV, INST PHYS, CS-12116 PRAGUE 2, CZECHOSLOVAKIA

[2] CHARLES UNIV, FAC MED, MED CLIN 1, CS-12808 PRAGUE 2, CZECHOSLOVAKIA

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY | 1990年 / 5卷 / 3-4期

关键词：

Hyperbaric oxygenation; photo-oxidation of bilirubin; photodynamic therapy; phototherapy of jaundice; porphyrin-sensitized photo-oxidation;

D O I：

10.1016/1011-1344(90)85045-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Oxygen concentration controls the reaction rate of porphyrin-sensitized photo-oxidation under constant experimental conditions. The rate of bilirubin and ditaurobilirubin auto-oxidation and meso-tetra-(4-sulphonatophenyl)porphine-sensitized photo-oxidation in aqueous solution increases by about 3.5 times in 0.5 MPa of oxygen. Use of hyperbaric oxygenation in the photodynamic therapy of tumours and in the phototherapy of jaundice is proposed. © 1990.

引用

页码：295 / 302

页数：8

共 31 条

[1] A SIMPLIFIED SYNTHESIS FOR MESO-TETRAPHENYLPORPHIN [J].