PRENATAL-DIAGNOSIS OF ALPHA-1-ANTITRYPSIN DEFICIENCY BY PCR OF LINKED POLYMORPHISMS - A STUDY OF 17 CASES

被引：5

作者：

ABBOTT, CM ^{[1
]}

LOVEGROVE, JU ^{[1
]}

WHITEHOUSE, DB ^{[1
]}

HOPKINSON, DA ^{[1
]}

POVEY, S ^{[1
]}

机构：

[1] UNIV LONDON UNIV COLL,GALTON LAB,MRC,HUMAN BIOCHEM GENET UNIT,LONDON NW1 2HE,ENGLAND

来源：

PRENATAL DIAGNOSIS | 1992年 / 12卷 / 04期

关键词：

ALPHA-1-ANTITRYPSIN; CVS; PCR;

D O I：

10.1002/pd.1970120402

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We describe our experiences of prenatal diagnosis of alpha-1-antitrypsin deficiency using closely linked polymorphisms detected by Southern blotting and the polymerase chain reaction. Prenatal diagnosis was carried out for 17 pregnancies from 15 couples.

引用

页码：235 / 240

页数：6

共 11 条

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