MR OBSERVATIONS ON THE EFFECTS OF PRAZIQUANTEL IN NEUROCYSTICERCOSIS

被引：16

作者：

JENA, A

SANCHETEE, PC

TRIPATHI, R

JAIN, RK

GUPTA, AK

SAPRA, ML

机构：

[1] NMR Research Centre, Institute of Nuclear Medicine and Allied Sciences, Delhi, 110054, Lucknow Marg

[2] Neuro Centre, Army Hospital, New Delhi, 110010, Delhi Cantt

来源：

MAGNETIC RESONANCE IMAGING | 1992年 / 10卷 / 01期

关键词：

MRI; PRAZIQUANTEL; EFFECTS; NEUROCYSTICERCOSIS;

D O I：

10.1016/0730-725X(92)90375-A

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Eight patients with neurocysticercosis treated with praziquantel (PZQ) were studied with serial MR imaging to demonstrate the early effects of the drug in brain lesions. Increase in cyst size and appearance of pericystic edema were observed as early as 24 hr, followed by gradual degeneration of the scolex and cyst contents. Cysts showed varied degree of response to the drug and in their rate of disappearance. MRI was found to be a sensitive technique to objectively document early changes in the parasite and patterns of response to the cysticidal drug in brain cysticercosis.

引用

页码：77 / 80

页数：4

共 11 条

[1]

Tandon, Cerebral cysticercosis, Neurosurg. Rev., 6, pp. 119-127, (1983)

[2]

Botero, Castano, Treatment of cysticercosis with praziquantel in Columbia, Am. J. Trop. Med. Hyg., 31, pp. 811-821, (1982)

[3]

Bell, Cysticercosis: A new hope, Br. Med. J., 289, pp. 857-858, (1984)

[4]

Thomas, Andrews, Mehlhorn, New results on the effects of praziquantel in experimental cysticercosis, Am J. Trop. Med. Hyg., 31, pp. 803-810, (1982)

[5]

Vanconcelos, Cruz Segura, Gomez, Alanis, Selective indications for the use of praziquantel in the treatment of brain cysticercosis., Journal of Neurology, Neurosurgery & Psychiatry, 50, pp. 383-388, (1987)

[6]

Soltelo, Escabedo, Rodrigugz-Carbajal, Torres, Rubio-Donnadieu, Therapy of Parenchymal Brain Cysticercosis with Praziquantel, New England Journal of Medicine, 310, pp. 1001-1007, (1984)

[7]

Van Dellan, McKeown, Praziquantel in active cerebral cysticercosis, J. Neurosurg., 22, pp. 92-96, (1988)

[8]

Jena, Sanchetee, Gupta, Khushu, Chandra, Lakshimipathi, Cysticercosis of the brain shown by magnetic resonance imaging, Clin. Radiol., 39, pp. 542-546, (1988)

[9]

Ramos, Stiebel-Chin, Atman, Duchoway, Diagnosis of neurocysticercosis by magnetic resonance imaging, Pediatr. Infect. Dis. J., 5, pp. 470-473, (1986)

[10]

Suss, Maravilla, Thompson, MR imaging of intracranial cysticercosis: Comparision with CT and anatomopathological features, AJNR, 7, pp. 235-242, (1986)

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