SYNTHESIS OF THE PRELOG-DJERASSI LACTONE AND PROTOMYCINOLIDE-IV BASED ON THE STEREOSPECIFIC METHYLATION OF GAMMA,DELTA-EPOXY ACRYLATES BY TRIMETHYLALUMINUM

被引：14

作者：

MIYASHITA, M ^{[1
]}

HOSHINO, M ^{[1
]}

YOSHIKOSHI, A ^{[1
]}

KAWAMINE, K ^{[1
]}

YOSHIHARA, K ^{[1
]}

IRIE, H ^{[1
]}

机构：

[1] TOHOKU UNIV, CHEM RES INST NON AQUEOUS SOLUT, AOBA KU, SENDAI, MIYAGI 980, JAPAN

来源：

CHEMISTRY LETTERS | 1992年 / 06期

关键词：

D O I：

10.1246/cl.1992.1101

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Prelog-Djerassi lactone, a key intermediate for the synthesis of several medicinally important macrolide antibiotics, and protomycinolide IV, a 16-membered macrolide, have been synthesized by employing the recently developed stereospecific methylation of gamma,delta-epoxy acrylates by trimethylaluminum as key steps.

引用

页码：1101 / 1104

页数：4

共 17 条

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