BIOSYNTHESIS OF VITAMIN-B12 IN PSEUDOMONAS-DENITRIFICANS - THE BIOSYNTHETIC SEQUENCE FROM PRECORRIN-6Y TO PRECORRIN-8X IS CATALYZED BY THE COBL GENE-PRODUCT

被引：42

作者：

BLANCHE, F

FAMECHON, A

THIBAUT, D

DEBUSSCHE, L

CAMERON, B

CROUZET, J

机构：

[1] RHONE POULENC RORER SA,INST BIOTECHNOL,F-94403 VITRY,FRANCE

[2] RHONE POULENC RORER SA,CTR RECH VITRY ALFORTVILLE,F-94403 VITRY,FRANCE

来源：

JOURNAL OF BACTERIOLOGY | 1992年 / 174卷 / 03期

关键词：

D O I：

10.1128/jb.174.3.1050-1052.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A protein catalyzing methylation at C-5 and C-15 and decarboxylation of the acetic acid side chain at C-12 on precorrin-6y to yield precorrin-8x was purified to homogeneity from a recombinant strain of Pseudomonas denitrificans. It was sequenced at the N terminus and shown to be encoded by the cobL gene.

引用

页码：1050 / 1052

页数：3

共 14 条

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[5] NUCLEOTIDE-SEQUENCE OF A PSEUDOMONAS-DENITRIFICANS 5.4-KILOBASE DNA FRAGMENT CONTAINING 5 COB GENES AND IDENTIFICATION OF STRUCTURAL GENES ENCODING S-ADENOSYL-L-METHIONINE - UROPORPHYRINOGEN-III METHYLTRANSFERASE AND COBYRINIC ACID A,C-DIAMIDE SYNTHASE
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