EFFECTS OF PHALLOIDIN ON K+-DEPENDENT, CA2+-INDEPENDENT NEUROTRANSMITTER EFFLUX AND K+-FACILITATED, CA2+-DEPENDENT NEUROTRANSMITTER RELEASE

被引：6

作者：

BABITCH, JA

GAGE, FH

VALDES, JJ

机构：

[1] Chemistry of Behavior Program, Texas Christian University Fort Worth

来源：

LIFE SCIENCES | 1979年 / 24卷 / 02期

关键词：

D O I：

10.1016/0024-3205(79)90120-6

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Phalloidin tightly binds to actin and converts soluble actin into depolymerization-resistant actin filaments. Phalloidin promotes the potassium-dependent, calcium-independent efflux of γ-amino butyric acid and nore-pinephrine from synaptosomes but inhibits the potassium-facilitated, calcium-dependent release of these neurotransmitters. This suggests that an actomyosin system is involved in synaptic transmission. © 1979.

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页码：117 / 124

页数：8

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