UNUSUAL DIFFERENCE SPECTRA OF PROTEINS CONTAINING TRYPTOPHAN .2. STUDIES WITH PROTEINS

被引:77
作者
ANANTHANARAYANAN, VS
BIGELOW, CC
机构
[1] Department of Biochemistry, University of Western Ontario
关键词
D O I
10.1021/bi00837a035
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An attempt is made to interpret unusual difference spectra observed with various tryptophyl-containing proteins in a consistent fashion working from studies made with model compounds. It is found that an analysis of the behavior of the hitherto ignored extremum around 300 mμ in these difference spectra can yield information about the electrostatic environment of tryptophyl residues in the native form of the proteins and about small local conformational changes around these residues which take place under certain conditions in some of these proteins. © 1969, American Chemical Society. All rights reserved.
引用
收藏
页码:3723 / +
页数:1
相关论文
共 29 条
[1]   UNUSUAL DIFFERENCE SPECTRA OF PROTEINS CONTAINING TRYPTOPHAN .I. STUDIES WITH MODEL COMPOUNDS [J].
ANANTHANARAYANAN, VS ;
BIGELOW, CC .
BIOCHEMISTRY, 1969, 8 (09) :3717-+
[2]  
BIGELOW C C, 1960, C R Trav Lab Carlsberg, V31, P283
[3]   EFFECT OF DODECYL SULFATE ON ULTRAVIOLET SPECTRA OF PROTEINS [J].
BIGELOW, CC ;
SONENBERG, M .
BIOCHEMISTRY, 1962, 1 (02) :197-&
[4]   ON CONFORMATION OF HEN EGG-WHITE LYSOZYME MOLECULE [J].
BLAKE, CCF ;
MAIR, GA ;
NORTH, ACT ;
PHILLIPS, DC ;
SARMA, VR .
PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1967, 167 (1009) :365-+
[6]   EFFECTS OF CHARGED GROUPS ON CHROMOPHORES OF LYSOZYME AND OF AMINO ACIDS [J].
DONOVAN, JW ;
LASKOWSKI, M ;
SCHERAGA, HA .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1961, 83 (12) :2686-&
[8]  
EDSALL JT, 1966, BIOCHEM Z, V345, P9