N-SUBSTITUTED-2-AMINO-2-METHYL-1-PROPANOLS AS POTENTIAL ANTITUMOR AGENTS

被引：9

作者：

BILLMAN, JH

KOEHLER, F

MAY, R

机构：

[1] Department of Chemistry, Indiana University, Bloomington, Indiana

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1969年 / 58卷 / 06期

关键词：

2‐Amino‐2‐methyl‐1‐propanols; N‐substituted—synthesis; Antitumor activity—Schiff bases; IR spectrophotometry—structure; NMR spectroscopy—structure; Schiff‐base derivatives—2‐amino‐2‐methyl‐1‐propanols;

D O I：

10.1002/jps.2600580630

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Twenty‐seven Schiff‐base derivatives of 2‐amino‐2‐methyl‐1‐propanol have been prepared and submitted for antitumor testing. Thirteen N‐substituted‐2‐amino‐2‐methyl‐1‐propanols were prepared by the reduction of the above Schiff bases. These also were submitted for antitumor testing. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：767 / &

共 5 条

[1] THE OXAZOLIDINES [J].