IMPROVED DETECTION OF IMMUNE-COMPLEXES IN HUMAN AND MOUSE SERUM USING A MICRO-ASSAY ADAPTATION OF THE C1Q BINDING TEST

被引：12

作者：

JUNE, CH ^{[1
]}

CONTRERAS, CE ^{[1
]}

PERRIN, LH ^{[1
]}

LAMBERT, PH ^{[1
]}

机构：

[1] HOP CANTONAL,CTR TRANSFUS,WHO,CTR IMMUNOL RES & TRAINING,CH-1211 GENEVA 4,SWITZERLAND

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1979年 / 31卷 / 1-2期

关键词：

D O I：

10.1016/0022-1759(79)90282-5

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A microassay adaptation of the [125I]C1q binding test for the detection of circulating immune complexes is described. This technique is more rapid to perform, requires smaller volumes of serum and reagents, and surprisingly, increases the sensitivity of the assay when compared to the previously reported C1q binding method. © 1979.

引用

页码：23 / 29

页数：7

共 7 条

[1]

CARPENTIER NA, 1978, MANUAL TECHNIQUES IM, P75

[2]

CASALI P, 1977, CLIN EXP IMMUNOL, V29, P342

[3]

HEUSSER C, 1973, J IMMUNOL, V110, P820

[4]

LAMBERT PH, 1978, J CLIN LAB IMMUNOL, V1, P1

[5] CIRCULATING IMMUNE-COMPLEXES IN SERUM IN SYSTEMIC LUPUS-ERYTHEMATOSUS AND IN CARRIERS OF HEPATITIS-B ANTIGEN - QUANTITATION BY BINDING TO RADIOLABELED CLQ [J].

NYDEGGER, UE ;

LAMBERT, PH ;

GERBER, H ;

MIESCHER, PA .

JOURNAL OF CLINICAL INVESTIGATION, 1974, 54 (02) :297-309

[6]

ZUBLER RH, 1976, J IMMUNOL, V116, P232

[7]

ZUBLER RH, 1976, IN VITRO METHODS CEL, P565

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