POLYMORPHONUCLEAR LEUKOCYTE MOTILITY IN VITRO .3. POSSIBLE RELEASE OF A CHEMOTACTIC SUBSTANCE AFTER PHAGOCYTOSIS OF URATE CRYSTALS BY POLYMORPHONUCLEAR LEUKOCYTES

被引：58

作者：

PHELPS, P

机构：

[1] University of Pennsylvania, Philadelphia, Pennsylvania

[2] General Clinical Research Center, Philadelphia General Hospital, Philadelphia, 19104, Building 25

来源：

ARTHRITIS AND RHEUMATISM | 1969年 / 12卷 / 03期

关键词：

D O I：

10.1002/art.1780120306

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The mechanism whereby polymorphonuclear leukocytes (PMN's) are attracted to the site of inflammation in gout is not known. Studies were performed, using a modification of the Boyden chamber technic, to determine whether phagocytosis of monosodium urate crystals by PMN's would result in release of a substance chemotactic for other PMN's. The supernatant from a PMN‐crystal suspension, in both a plasma and a plasma‐free solution containing albumin, was found to be chemotactic for PMN's. Copyright © 1969 American College of Rheumatology

引用

页码：197 / &

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