STUDIES OF THE SOLUBILITY OF DIFFERENT CALCIUM-PHOSPHATE CERAMIC PARTICLES INVITRO

被引:154
作者
KLEIN, CPAT [1 ]
DEBLIECKHOGERVORST, JMA [1 ]
WOLKE, JGC [1 ]
DEGROOT, K [1 ]
机构
[1] LEIDEN STATE UNIV,SCH MED,DEPT BIOMAT,BIOMAT RES GRP,2312 AV LEIDEN,NETHERLANDS
关键词
bioceramics; Calcium phosphate; solubility;
D O I
10.1016/0142-9612(90)90067-Z
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In vitro solubility tests of hydroxyapatite, tetracalcium phosphate or tricalcium phosphate particles were performed in lactate, citrate, Gomoris or Michaelis buffer with pH 6.2 or 7.2 and in aqua destillata. The results showed that in general the solubility decreased in the order tetracalcium phosphate > tricalcium phosphate > hydroxyapatite, except for lactate or citrate buffer where the solubility order was tetracalcium phosphate = tricalcium phosphate > hydroxyapatite. The influence of the specific buffer used is much larger than either pH or specific calcium phosphate salt tested. The pH stability of lactate buffer and aqua destillata is very low, the other buffer solvents had a rather stable pH value. © 1990.
引用
收藏
页码:509 / 512
页数:4
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