PRIMARY SEQUENCE OF -1436 TO +53 BP OF THE RAT PREPROENKEPHALIN GENE PUTATIVE Z-DNA AND REGULATORY MOTIFS

被引：12

作者：

DURKIN, RC

WEISINGER, G

HOLLOWAY, MP

LAGAMMA, EF

机构：

[1] SUNY STONY BROOK,DEPT PEDIAT,HSC 11-060,STONY BROOK,NY 11794

[2] SUNY STONY BROOK,DEPT NEUROBIOL & BEHAV,STONY BROOK,NY 11794

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1131卷 / 03期

关键词：

Z-DNA; TRANSCRIPTIONAL CONTROL; PREPROENKEPHALIN GENE; (RAT);

D O I：

10.1016/0167-4781(92)90040-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report novel sequence data extending - 1436 bases 5' of the rat proenkephalin gene start site known as E4. We noted an interesting stretch of 58 bases of alternating pyrimidines that lies immediately adjacent to 71 bases of an alternating purine-pyrimidine Z-DNA-like sequence that lies between - 694 bp and - 566 bp. Multiple sequence homologies to putative cis-acting regulatory factor binding sites were identified by a computer aided sequence search.

引用

页码：349 / 351

页数：3

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