A COMPARISON OF INDUCED HEAT-SHOCK PROTEIN IN NEURONS DESTINED TO SURVIVE AND THOSE DESTINED TO DIE AFTER TRANSIENT ISCHEMIA IN RATS

被引：36

作者：

TOMIOKA, C ^{[1
]}

NISHIOKA, K ^{[1
]}

KOGURE, K ^{[1
]}

机构：

[1] TOHOKU UNIV, SCH MED, INST BRAIN DIS, DEPT NEUROL, AOHA KU, SENDAI, MIYAGI 980, JAPAN

来源：

BRAIN RESEARCH | 1993年 / 612卷 / 1-2期

关键词：

CEREBRAL ISCHEMIA; HEAT-SHOCK PROTEIN-72; RAT;

D O I：

10.1016/0006-8993(93)91663-D

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We examined the induction of heat-shock protein (HSP) in CA-1 pyramidal neurons compared with that in CA-3 pyramidal neurons, in rat brain following 20 min of ischemia. The time course of the changes of localization of HSP was investigated using immunohistochemical and Western blot analyses. The induction of HSP in the CA-1 subfield was the same as that in the surviving hippocampal CA-3 subfield.

引用

页码：216 / 220

页数：5

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