SOME COMPLEXES OF 2.3-DIMERCAPTOPROPANOL (BAL) WITH GOLD(I) AND GOLD(III)

被引：10

作者：

BROWN, DH

MCKINLAY, GC

SMITH, WE

机构：

[1] Department of Pure and Applied Chemistry, University of Strathclyde, Glasgow, G1 1XL, Cathedral Street

来源：

JOURNAL OF INORGANIC BIOCHEMISTRY | 1979年 / 10卷 / 04期

关键词：

D O I：

10.1016/S0162-0134(00)80194-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

2, 3-Dimercaptopropanol (BAL) reacted with the tetrachloroaurate ion in solution to form a series of insoluble polymers of definite stoichiometry. Both gold(I) and gold(III) have been identified in these compounds. Reaction of BAL with the tetrabromoaurate ion and with thiomalic acid and D-penicillamine complexes of gold also produced insoluble precipitates. However, with an L-cysteine complex of gold no precipitate was isolated, although there was evidence of replacement of cysteine with BAL. The implications of these results for the use of BAL in cases of gold toxicity are discussed. © 1979.

引用

页码：275 / 279

页数：5

共 14 条

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