SEQUENTIAL AUTONOMIC FUNCTION-TESTS IN HIV-INFECTION

被引:14
作者
SCOTT, G [1 ]
PIAGGESI, A [1 ]
EWING, DJ [1 ]
机构
[1] UNIV EDINBURGH,ROYAL EDINBURGH INFIRM,DEPT MED,EDINBURGH EH10 5HF,MIDLOTHIAN,SCOTLAND
基金
英国惠康基金;
关键词
HIV INFECTION; AUTONOMIC NEUROPATHY; AUTONOMIC FUNCTION TESTS;
D O I
10.1097/00002030-199012000-00017
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Cardiovascular autonomic function tests were carried out on 22 men at varying stages of HIV infection. Thirteen were asymptomatic, seven had persistent generalized lymphadenopathy, and two had Kaposi's sarcoma. Pupil cycle times were also measured. Except for one subject with definite autonomic abnormalities, all the rest had almost normal test results. There were no correlations between individual tests of immune function and the autonomic test results. The tests were repeated 9-18 months later in 12 men, four of whom were taking zidovudine at the time. Although there was evidence of progression of HIV-associated immune dysfunction, there was no significant deterioration in autonomic function. In the single patient with abnormal autonomic function, these changes appeared to reverse on treatment with zidovudine.
引用
收藏
页码:1279 / 1281
页数:3
相关论文
共 16 条
[1]  
Bredesen D.E., Levy R.M., Rosenblum M.L., The neurology of human immunodeficiency virus infection, Q J Med, 68, pp. 665-677, (1988)
[2]  
Lin-Greenberg A., Taneja Uppal N., Dysautonomia and infection with the human immunodeficiency virus, Ann Intern Med, 106, (1987)
[3]  
Craddock C., Pasvol G., Bull R., Protheroe A., Hopkins J., Cardiorespiratory arrest and autonomic neuropathy in AIDS, Lancet, 2, pp. 16-18, (1987)
[4]  
Villa A., Foresti V., Confalonieri F., Autonomic neuropathy and HIV infection, Lancet, 2, (1987)
[5]  
Miller R.F., Semple S.J.G., Autonomic neuropathy in AIDS, Lancet, 2, pp. 343-344, (1987)
[6]  
Evenhouse M., Haas E., Snell E., Visser J., Pawl L., Gonzalez R., Hypotension in infection with the human immunodeficiency virus, Ann Intern Med, 107, pp. 598-599, (1987)
[7]  
Mulhall B.P., Jennens I., Testing for neurological involvement in HIV infection, Lancet, 2, pp. 1531-1532, (1987)
[8]  
Cohen J.A., Laudenslager M., Autonomic nervous system involvement in patients with human immunodeficiency virus infection, Neurology, 39, pp. 1111-1112, (1989)
[9]  
Freeman R., Roberts M.S., Friedman L.S., Broadbridge C., Autonomic function and human immunodeficiency virus infection, Neurology, 40, pp. 575-580, (1990)
[10]  
Griffin G.E., Miller A., Batman P., Et al., Damage to jejunal intrinsic autonomic nerves in HIV infection, AIDS, 2, pp. 379-382, (1988)