GEOMETRICAL ISOMERISM OF THE O-SUBSTITUTED OXIMES OF SOME KETO-STEROIDS

被引：9

作者：

BODOR, A ^{[1
]}

BARABAS, A ^{[1
]}

机构：

[1] INST CHEM,R-3400 CLUJ,ROMANIA

来源：

TETRAHEDRON | 1979年 / 35卷 / 02期

关键词：

D O I：

10.1016/S0040-4020(01)99487-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

O-Benzyl- and/or O-iso-propyl-oximes of a number of 3-, 7- or 20-oxo-steroids and of some 3,20-di-oxosteroids have been prepared. The products were characterized by their C,H,N-content and physical properties and studied by UV, 1H- and 13C-NMR spectroscopy. The ketoximes of 3-oxo-Δ4-steroids were invariably found to consist of a mixture of two geometrical isomers, denominated syn and anti. In some cases both isomers could be obtained in a pure state by column-chromatography. Oximes of the 7-oxo-Δ5-steroids were found to consist only of the syn isomer, whereas the 20-oximino compounds showed no isomerism. © 1979.

引用

页码：233 / 240

页数：8

共 17 条

[1]

BHACCA NS, 1964, APPLICATIONS NMR SPE

[2]

CONDON R, 1974, STEROIDS, V23, P484

[3]

DIASSI PA, 1969, Patent No. 1906560

[4] C-13 NUCLEAR MAGNETIC-RESONANCE SPECTRA OF KETO STEROIDS [J].